NGR peptide Trifluoroacetate
CAS No.
NGR peptide Trifluoroacetate ( )
Catalog No. M30469 CAS No.
NGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameNGR peptide Trifluoroacetate
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NoteResearch use only, not for human use.
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Brief DescriptionNGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature.
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DescriptionNGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature.(In Vitro):NGR peptide can selectively bind to APN/CD13 either immune-captured or expressed on the surface of cells, the receptor of the tumor-homing NGR peptide was suspected to be APN/CD13. The NGR peptide is reported to have the greatest tumor selectivity. An anti-cancer drug Doxorubicin (DOX) coupled to an NGR peptide displays enhanced anti-tumor effects with even lower toxicity than the free drug itself.(In Vivo):NGR peptide imaging in vivo not only provides more insight into NGR’s targeting process, including bio-distribution and pharmacokinetics, but also reveals angiogenic activities related to tumor progression and malignancy.
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Synonyms
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PathwayOthers
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TargetOther Targets
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RecptorCD13/aminopeptidase N (APN) receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight722.7
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Molecular FormulaC22H37F3N10O10S2
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Purity>98% (HPLC)
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SolubilityH2O : ≥ 100 mg/mL (138.37 mM)
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SMILES——
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Enyedi KN, et al. NGR-peptide-drug conjugates with dual targeting properties. NGR-peptide-drug conjugates with dual targeting properties.
molnova catalog
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